Dose sparing and the history of the fight to control pox viruses
How the bifurcated needle accelerated the eradication of smallpox
In a press conference today, FDA Commissioner Robert Califf said the agency was considering whether Jynneos, the only vaccine licensed to prevent monkeypox, could be given intradermally. If approved, the approach would use just one-fifth of the dose, enabling a dramatic expansion of our constrained supply.
This is an interesting bit of parallel history. …
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